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ZO Peptide Facial Refining 30ml
ZO Peptide Facial Refining Concentrate - now available in clinic
Product Overview
Peptide Facial Refining Concentrate is ZO Skin Health’s advanced anti-ageing serum launched in September 2025, designed to complement the visible effects of neurotoxins and dermal fillers while also as a powerful standalone . This concentrated multiple signs of ageing four cutting-edge technologies, clinically proven to a more appearance and refined facial geometry in just 12 weeks.
Key Benefits
Targets and Volume Loss: The addresses both visible expression lines (dynamic wrinkles) and static wrinkles whilst the appearance of lost volume, creating a lifted and more .
Injectable Treatments: Designed to work synergistically with (like Botox) and dermal fillers, helping patients maintain between clinic visits whilst delivering visible on its own.
Supports Skin Structure: The Refining improves the appearance of skin’s structural integrity, more facial geometry. The Volumizing supports the skin’s natural production of acid for a plumper, fuller look.
Reduces Visible Redness: The exclusive ZPOLY™ helps to redness and the skin’s protective barrier.
Clinical Results
In a 12-week clinical study involving 49 aged with skin types I-VI:
92% saw a in the of fine lines
84% reported visibly younger-looking facial geometry (a more sculpted, balanced face overall)
86% saw improvement in facial hollow areas (places that had lost fullness)
82% experienced reduced wrinkles
96% said their skin felt smoother
Additional measurements showed:
10% reduction in volume after 4 weeks
11% improvement in skin texture after 12 weeks
8% improvement in skin firmness and elasticity after 2 weeks
12% in by week 12
100% of showed improvement in skin by week 4
Advanced Peptide Technologies
The formula is powered by four technologies:
1. Acetyl Octapeptide-3
Contains 8 amino acids
the appearance of lines and wrinkles, especially around the forehead and eye area
Functions as a neuropeptide to modulate wrinkle formation
2. Acetyl Hexapeptide-8
Contains 6 amino acids
Works synergistically with Acetyl Octapeptide-3
Provides in the of deeper dynamic and static wrinkles
3. Complex
Blend of 2 active peptides: Palmitoyl Dipeptide-5 Diaminobutyroyl and Palmitoyl Dipeptide-5 Diaminohydroxybutyrate
a visibly more facial geometry
the appearance of skin’s structural integrity
4. Tripeptide ( Urea Trifluoroacetate)
A unique tri-peptide
Supports the skin’s natural production of hyaluronic acid for fuller, plumper-looking skin
Helps restore the of lost volume
ZPOLY™ Complex
This ZO-exclusive, polysaccharide complex is a blend of four polysaccharide extracts:
Laminaria digitata (brown seaweed) extract
ficus-indica ( pear) stem cell extract
Schizophyllan (mushroom)
Galactoarabinan (larch tree)
Benefits: Helps signs of ageing, skin restoration, boosts after a single application, and minimises the appearance of and blotchiness for a calm skin tone.
Full Ingredient List
Aqua/Water/Eau, Cyclopentasiloxane, Glycol, Glycol, Dimethicone, Glycerin, Crosspolymer, Dimethicone/PEG-10/15 Crosspolymer, PEG-12 Crosspolymer, Glycol, Dimethicone/Vinyl Crosspolymer, Sodium Phosphate, Triacetate, Phospholipids, Magnesium Sulfate, Sericin, Ethyl Linoleate, Meristem Cell Culture, Angelica Polymorpha Sinensis Root Extract, Dipeptide Diaminobutyroyl Diacetate, Lactobacillus/Panax Ginseng Root Extract Ferment Filtrate, Disodium Acetyl Phosphate, Acetyl Tyrosine, Dimethiconol, Oleyl Alcohol, Proline, (Parfum), Tocopherol, Beta-Glucan, Triphosphate, Hydrolyzed Protein, Sodium Chloride, Gum, Phenoxyethanol.
Formulation Properties
Alcohol-free and fragrance-free (though some sources list "Fragrance (Parfum)" in the full list)
Silicone-based serum with a lightweight, smooth texture
Suitable for all skin types
Makes it a perfect to procedures
How to Use
Application: Apply 1-2 pumps to clean, dry skin
Frequency: Morning and/or evening.
Placement: Apply before moisturiser for results. As a serum, it should be applied after and toning but before heavier creams or SPF
Pairing: Can be with Serum and AOX Serum for enhanced anti-ageing results
Ideal Candidates
This serum is particularly for those who:
Are both dynamic lines (from facial movement) and static lines ( when the face is relaxed)
Have signs of lost volume (around cheeks, under the eyes, or facial hollows) and want resorting to fillers
Would like to or from like fillers or Botox
Want to improve skin texture, firmness, and contour over time
Are seeking a high-performance solution with clinical backing
Before and afters
Results may vary from person to person, based on personalised Skin plans.
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